A vaccine for Lassa fever may be on the horizon, thanks to a new clinical trial jointly led by Elissa Malkin, DO, MPH, assistant research professor of medicine at the George Washington University School of Medicine and Health Sciences. With an award from trial sponsor IAVI, Malkin, along with collaborators from Brigham and Women’s Hospital in Boston, Redemption Hospital in Monrovia, Liberia, and East-West Medical Research Institute in Honolulu, Hawaii, will be testing IAVI’s experimental vaccine candidate called “rVSV∆G-LASV-GPC,” a recombinant vesicular stomatitis virus (rVSV) vector-based vaccine expressing a Lassa virus protein (LASV-GPC).
SMHS-Led Clinical Trial To Assess Immunogenicity and Safety of Lassa Fever Vaccine
Latest News
This was a phase 2, randomized, open-label, non-placebo controlled trial to evaluate two partial doses o the Modified Vaccinia Ankara-Bavarian Nordin (MVA-BN) vaccine for protection against mpox.
This was a phase 1, double-blind trial to examine the safety and immunogenicity of a replication-competent recombinant vesicular stomatitis virus-vectored vaccine to reduce the risk of infection and severe illness from Lassa Fever.
The GW VRU is pleased to share the findings from a Phase 2 clinical trial that evaluated the effects of omicron-based COVID-19 vaccines in providing an increased level of protection against COVID-19 infection. This study adds to the evidence that matching COVID-19 vaccines to the circulating…